Treatment of Narcolepsy and other Hypersomnias of Central Origin An American Academy of Sleep Medicine Review
نویسنده
چکیده
1.0 Introduction 1.1 Purpose 1.2 Causes of excessive sleepiness 2.0 Background 3.0 Methods 3.1 Literature search strategy 3.2 Evidence review 4.0 Results 4.1 Treatment of hypersomnia due to narcolepsy with or without cataplexy 4.1.1 Medications 4.1.1.1 Amphetamine, methamphetamine, dextroamphetamine methylphenidate, and related preparations 4.1.1.2 Modafinil and armodafinil 4.1.1.3 Sodium oxybate 4.1.1.4 Selegiline 4.1.1.5 Reboxetine 4.1.1.6 Ritanserin 4.1.1.7 Pemoline 4.1.2 Scheduled naps plus stimulants versus stimulants alone 4.2 Treatment of cataplexy 4.2.1 Sodium oxybate 4.2.2 Medications other than sodium oxybate 4.3 Treatment of disrupted nocturnal sleep associated with narcolepsy 4.3.1 Sodium oxybate 4.3.2 Hypnotic medications 4.4 Treatment of hypnagogic hallucinations and sleep paralysis associated with narcolepsy 4.4.1 Sodium oxybate 4.4.2 Antidepressant medications 4.5 Studies with quality of life data 4.6 Treatment of hypersomnia associated with narcolepsy due to medical conditions 4.7 Treatment of hypersomnia due to recurrent hypersomnia Treatment of Narcolepsy and other Hypersomnias of Central Origin
منابع مشابه
Excessive Daytime Sleepiness Has a Significant Detrimental Impact on Psychological, Social and Vocational Function and Personal Safety,
EXCESSIVE DAYTIME SLEEPINESS HAS A SIGNIFICANT DETRIMENTAL IMPACT ON PSYCHOLOGICAL, SOCIAL AND VOCATIONAL FUNCTION AND PERSONAL SAFETY, thus adversely affecting quality of life. Sleepiness is an important public health issue among individuals who work in fields where the lack of attention can result in injury to self or others such as transportation and healthcare. Hypersomnia of central origin...
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OBJECTIVE The purpose of this paper is to summarize current knowledge about treatment of narcolepsy and other hypersomnias of central origin. METHODS The task force performed a systematic and comprehensive review of the relevant literature and graded the evidence using the Oxford grading system. This paper discusses the strengths and limitations of the available evidence regarding treatment o...
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